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Researchers show effective oral treatment option for patients with rheumatoid arthritis


Patients suffering from rheumatoid arthritis are treated for around six months with the standard anti-rheumatic agent methotrexate, to which many patients respond very well. However, if they do not respond and no remission or at least reduction in the activity of the disease can be achieved, they are given a combined treatment of methotrexate and a biologic agent (frequently an anti-TNF, such as e.g. adalimumab, administered by injection), if risk factors are present. An international research group has now shown that there is another, equally effective oral treatment option: the combination of methotrexate and the chemically synthesized Janus Kinase Inhibitor tofacitinib. The results of the study, for which MedUni Vienna rheumatologist Josef Smolen was senior author, have now been published in top medical journal “The Lancet”.

Smolen, Head of the Division of…



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